SiliaBond® Chromatographic and Ion Exchange Silica Gels

flash columnThe sorbent required for the purification of a specific substrate will vary according to the structure of the said substrate.  Weather it is ionized or neutral and depending on its polarity and solubility, the appropriated chromatographic stationary phase will vary.  In order to better fulfill those different needs, SiliCycle offer a wide variety of sorbents for normal and reversed-phase.  Please refer to the sorbent selection guide to select the most appropriated phase.

 Reversed Phases

Typical Applications:

  • C18 - Peptides, pesticides, PCBs, PAHs, toxins, drugs & their metabolites in physiological fluids
  • C8 - Highly hydrophobic pesticides, peptides, drugs and their metabolites in physiological fluids
  • C6 - Phenols, chloroanilines and anthelmintics from tissues and water
  • C4 - Molecules with large hydrophilic region such as peptides, proteins and zwitterions (300 Å)
  • C1 - Polar and non-polar pharmaceutical natural products and highly hydrophobic molecules
  • CN - Cyclosporine and carbohydrates
  • PHE - Aflatoxins, caffeine, and phenols from water
  • PFP - Conjugated compounds or for a new selectivity approach

All the below phases come bonded on a 40-63um, 60A Silica Particle. To order simply add the pack size your after to the end of the part number. pack sizes available are 5g, 10g, 25g, 50g, 100g, 250g, 500g 1Kg and 25Kg.

e.g. part number R33230B-1KG would be a 1Kg pack of 40-63um, 60A C18 (17%) Bonded Silica Gel.

Phases Available

Sorbent   Phase  Functional Group  Endcapping  %C Loading Part Number
 C18  Monofunctional C18  Yes   17 R33230B
 C18 nec Monofunctional C18 No   15.5 R33330B 
 C18 Low Loading  Monofunctional C18  Yes 11 R33530B
 C18 High Loading  Trifunctional C18  Yes  23 R30030B 
 C18 High Loading nec Trifunctional C18 No  23 R30130B 
 C18 Moderate Loading Trifunctional C18  Yes  17 R32130B
 C18 Low Loading  Trifunctional C18  Yes  11 R30430B 
 C12  Trifunctional Adamantyl Yes   16 R53030B
 C8  Monofunctional C8  Yes 11 R30830B 
 C8 Trifunctional C8 Yes   12 R31030B  
 C8 nec  Trifunctional C8  No  11 R31130B
 C6  Trifunctional Cyclohexyl Yes 10 R61530B 
 C4  Monofunctional C4 Yes  7-8.0  R32730B  
 C4  Trifunctional C4 Yes  8 R32030B
 C4 nec  Trifunctional C4 No   8 R32130B 
 C1   Methyl  Yes  5 R33030B 
 CN Trifunctional Cyano   Yes  7 R38030B  
 PHE Monofunctional Phenyl  Yes  9 R33830B 
 PHE Trifunctional Phenyl   Yes   9 R34030B 
 PHE nec  Trifunctional Phenyl No 9 R34130B 
 PFP  Pentafluorophenyl  Yes  9 R67530B  

 

Normal Phases

Typical Applications:

  • NH2 nec - Sugars, nucleotides and water-soluble vitamins
  • CN nec - Polar organic compounds such as basic drugs and molecules containing π electron systems
  • Diol nec - Peptides, proteins and malto-oligosaccharides
  • AgNO3 - Cis/trans isomers of unsaturated compounds such as alkenes, lipids, steroids and terpenes

All the below phases come bonded on a 40-63um, 60A Silica Particle. To order simply add the pack size your after to the end of the part number. pack sizes available are 5g, 10g, 25g, 50g, 100g, 250g, 500g 1Kg and 25Kg.

 e.g. part number R52130B-1KG would be a 1Kg pack of 40-63um, 60A NH2 bonded Silica Gel.

Phases Available

Sorbent Phase  Functional Group Endcapping  % Loading Part Number
 SiO2 Bare silica gel No N/A R10030B
 NH2 nec Amine No 1.6 R52130B
 CN nec Cyano No 1 R38130B
 Diol nec Diol No 1 R35030B
 AgNO3 Silver Nitrate No 10% w/w R23530B

 

Ion Exchange Phases

 All the below phases come bonded on a 40-63um, 60A Silica Particle. To order simply add the pack size your after to the end of the part number. pack sizes available are 5g, 10g, 25g, 50g, 100g, 250g, 500g 1Kg and 25Kg.

 e.g. part number R52130B-1KG would be a 1Kg pack of 40-63um, 60A NH2 bonded Silica Gel.

 Phases Available

Sorbent Phase  Functional Group  Endcapping  Loading (mmol/g)a  Part Number
WAX   Amine  No  1.6 R52130B
WAX-2  Diethylamine No  1.2 R76630B 
SAX   Trimethylammonium Chloride  No  1.1 R66230B 
SAX-2  Trimethylammonium Acetate  No  0.7 R66430B 
TBA Chloride  Tributylammonium Chloride  No  0.5 R65530B 
SCX   Tosic Acid  No   0.8 R60430B 
SCX-2  Propylsulfonic Acid   No   1 R51430B  
WCX Carboxylic Acid  No  1.4 R70130B