SiliaChrom AQ C18 HPLC Columns

SiliaChrom AQ C18 columns use a new generation adsorbent based on high purity spherical silica and unique bonding technology. SiliaChrom AQ C18 is a slightly polar C18 column, and is the most versatile reversed phase column offered by SiliCycle for highly aqueous mobile phases. SiliaChrom AQ C18 is considered as the most universal HPLC column for any type of analytes (acidic, basic and neutral). Furthermore, SiliaChrom AQ C18 is applicable to a wide range of sample types: plasma, urine, drug formulation, food extraction, forensic, clinical and bioanalytical.

• Exceptional stability at pH 1,5 to 9,0
• Inertness for acidic and basic analytes
• Compatible from 100% aqueous mobile phase to 100% organic
• Rapid equilibration
• Reduced need for mobile phase modifiers
• Partially endcapped

Evaluation of Resolution and Peak Shape of Acidic, Basic and Neutral Commercial Drugs

• SiliaChrom AQ C18, 5 µm, 4,6x150 mm (SiliCycle P/N: HPC-1405-15N)
• MPA: 5mM potassium monobasic (adjust to pH 2,5 with H₃PO₄)/ACN (90/10)
• MPB: 5mM potassium monobasic (adjust to pH 2,5 with H₃PO₄)/ACN (10/90)
• Gradient: MPA to MPB, 20 minutes
• Temperature: 23°C
• Flow rate: 1,0 mL/min
• Detector: UV at 230 nm
• Injection volume: 20 µL

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